Aravive Inc
Change company Symbol lookup
Select an option...
ARAV Aravive Inc
CBU Community Bank System Inc
FPA First Trust Asia Pacific Ex-Japan AlphaDEX® Fund
GER Goldman Sachs MLP and Energy Renaissance Fund
FNX First Trust Mid Cap Core AlphaDEX® Fund
FNK First Trust Mid Cap Value AlphaDEX® Fund
FMK First Trust Mega Cap AlphaDEX® Fund
FLN First Trust Latin America AlphaDEX® Fund
FKU First Trust United Kingdom AlphaDEX® Fund
FKO First Trust South Korea AlphaDEX® Fund
Go

Health Care : Biotechnology | Small Cap ValueCompany profile

Aravive, Inc., formerly Versartis, Inc., is a clinical-stage biotechnology company. The Company is focused on developing therapies that target survival pathways for both solid tumors, as well as hematologic malignancies. Its primary therapeutic focus is the growth arrest-specific 6 (GAS6) - AXL receptor tyrosine kinase (AXL) pathway, where AXL receptor signaling promotes metastasis, cancer cell survival, resistance to treatments and immune suppression. The Company’s lead candidate, Aravive-S6 (AVB-S6)-500, is a GAS6 binding protein and AXL decoy receptor. It is a Fc -chimeric fusion protein designed to block the activation of the Growth arrest-specific 6 (GAS6)-AXL signaling pathway by intercepting the binding of GAS6 to its receptor AXL. Its AXL decoy receptor is a protein based on the extracellular portion of AXL that binds its ligand GAS6, sequesters it from the native receptor and prevents AXLmediated signaling.

Closing Price
$8.26
Day's Change
0.4248 (5.42%)
Bid
--
Ask
--
B/A Size
--
Day's High
8.28
Day's Low
7.82
Volume
(Above Average)
Volume:
43,249

10-day average volume:
39,089
43,249

UPDATE: Canada is running out of marijuana

1:23 pm ET October 28, 2018 (MarketWatch)
Print

By Max A. Cherney

Quebec and Ontario, two of the largest provinces, suffering from shortages due to supply and postal strike just more than a week into sales

Just more than a week after Canada became the first G-7 nation to legalize marijuana for adult recreational use, provincial sellers are reporting supply shortages and other difficulties getting the product to consumers.

Federal government officials and executives at major marijuana producers around the country warned MarketWatch in past interviews that the first weeks -- even months -- would not run like clockwork following Oct. 17 legalization. The dearth of bricks-and-mortar retail locations in some of the country's largest provinces, a rotating national postal strike which has hampered online orders and a backlog in federal licensing have all worked together to exacerbate what was already a challenging undertaking.

"Yes, the long-eluded-to 'supply crunch' is now a reality," Deepak Anand, vice president of business development and government relations at marijuana-consulting company Cannabis Compliance Inc., said Friday. "Licensed producers are certainly looking to supply more product."

From earlier: Cannabis is now legal in Canada, but pot companies expect a rocky start (http://www.marketwatch.com/story/cannabis-is-now-legal-in-canada-but-pot-companies-expect-a-rocky-start-2018-10-17)

In Quebec, the country's second most populous province, the government said its offical store would only be open (https://twitter.com/La_SQDC/status/1055869257186230272) from Thursday to Sunday, closing the rest of the week because it didn't have enough pot to sell. The online store will remain open and the bricks-and-mortar retail closures will continue until further notice.

Quebec has set up agreements with only a handful of licensed producers, but even provinces with many more supply agreements suffered from issues.

The Ontario Cannabis Store, or OCS, an online retailer operated by the country's most populous province, Ontario, was receiving complaints online about delivery times and cancellations as well as quality of the product. Officials said the online store made 100,000 sales within the first 24 hours and as of Tuesday afternoon had processed 150,000 orders since Oct. 17. The OCS said it has enough pot to supply all the orders and continues to receive more.

Shortages and delivery issues around the country have been compounded by rotating strikes by the country's national post office Canada Post, which have affected different regions. For example, the post office told a Canadian newspaper (https://ottawacitizen.com/news/local-news/ontario-cannabis-store-apologizes-for-delays-blames-canada-post) that Toronto, the largest city by population in the country, is a "significant mail and processing hub" and striking workers are making the "best efforts to minimize any impact on service." Roughly 9,000 postal workers walked off the job (https://torontosun.com/news/provincial/unbelievably-high-demand-postal-woes-blamed-for-cannabis-delays-in-ontario) in Toronto on Tuesday.

Not every province has suffered from problems, however. New Brunswick sold C$2.1 million worth of cannabis (https://translate.google.com/translate?hl=en&sl=fr&u=https://ici.radio-canada.ca/nouvelle/1131845/cannabis-nb-modifie-site-internet-sante-canada-nouveau-brunswick&prev=search) the first week with few issues.

For the largest licensed producers, it's less clear how the shortages will affect the quarter's sales and profits. Buyers in Nova Scotia, which sells in government-run stores, and Alberta, which has deployed private retail stores in several cities, said that they had received about 40% of the weed they ordered from the country's licensed pot producers.

Don't miss: Canada's pot party includes big demand, short supply, and stamps with no glue (http://www.marketwatch.com/story/canadas-pot-party-big-demand-short-supply-and-stamps-with-no-glue-2018-10-20)

Major producers MarketWatch talked with in Canada last week such as Canopy Growth Corp. (WEED.T), Tilray Inc. and Cronos Group Inc.(CRON.T) were expecting issues to come up from the beginning.

"The system won't be perfect out of the gate, and we shouldn't expect it to be," Aurora Cannabis Inc (ACB.T) Chief Corporate Officer Cam Battley told MarketWatch in an interview last week. "It's a nationwide, very complex system with 13 jurisdictions, plus all of the municipalities. Are you kidding me? It's going to take a while to iron out, but it's going to be fine."

For new producers hoping to meet some of the demand, the road is not easier either. According to a Bloomberg report Friday (https://www.chicagotribune.com/business/ct-biz-canada-marijuana-demand-20181026-story.html), Health Canada may take take up to 341 days to process a new cannabis sales license application.

Marijuana stocks were mixed Friday (http://www.marketwatch.com/story/cannabis-stocks-on-track-for-sharp-losses-on-the-week-after-steep-selloff-2018-10-26) amid a sliding market and finished the week with sharp losses. The sector suffered seven straight days of declines before a slight recovery Thursday. The Horizons Marijuana Life Sciences exchange-traded fund fell nearly 17% this week as the S&P 500 index fell 3.9%.

-Max A. Cherney; 415-439-6400; AskNewswires@dowjones.com

(END) Dow Jones Newswires

October 28, 2018 13:23 ET (17:23 GMT)

Copyright (c) 2018 Dow Jones & Company, Inc.

Earnings Calendar and Events Data provided by |Terms of Use| © 2019 Wall Street Horizon, Inc.

Market data accompanied by is delayed by at least 15 minutes for NASDAQ, NYSE MKT, NYSE, and options. Duration of the delay for other exchanges varies.
Market data and information provided by Morningstar.

Options are not suitable for all investors as the special risks inherent to options trading may expose investors to potentially rapid and substantial losses.
Please read Characteristics and Risks of Standard Options before investing in options.

Information and news provided by ,, , Computrade Systems, Inc., , and

Copyright © 2019. All rights reserved.