Aravive Inc
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Health Care : Biotechnology | Small Cap ValueCompany profile

Aravive, Inc., formerly Versartis, Inc., is a clinical-stage biotechnology company. The Company is focused on developing therapies that target survival pathways for both solid tumors, as well as hematologic malignancies. Its primary therapeutic focus is the growth arrest-specific 6 (GAS6) - AXL receptor tyrosine kinase (AXL) pathway, where AXL receptor signaling promotes metastasis, cancer cell survival, resistance to treatments and immune suppression. The Company’s lead candidate, Aravive-S6 (AVB-S6)-500, is a GAS6 binding protein and AXL decoy receptor. It is a Fc -chimeric fusion protein designed to block the activation of the Growth arrest-specific 6 (GAS6)-AXL signaling pathway by intercepting the binding of GAS6 to its receptor AXL. Its AXL decoy receptor is a protein based on the extracellular portion of AXL that binds its ligand GAS6, sequesters it from the native receptor and prevents AXLmediated signaling.

Closing Price
$8.26
Day's Change
0.4248 (5.42%)
Bid
--
Ask
--
B/A Size
--
Day's High
8.28
Day's Low
7.82
Volume
(Above Average)
Volume:
43,249

10-day average volume:
39,089
43,249

Cannabis stocks are a green spot in a sea of red after reversing early losses

11:29 am ET November 20, 2018 (MarketWatch)
Print

Cannabis stocks reversed their early losses Tuesday to trade mostly higher, shrugging off the rout in the broader market which was falling as investors continued to sell off technology and internet stocks. Canopy Growth Corp. (WEED.T)led the gainers, adding 2.9% in midmorning trade. Canopy is viewed as one of the stronger players in the new sector, thanks to a $4 billion investment from drinks giant Constellation Brands Inc. (STZ). Cronos Corp. (CRON.T) was up 3.1%. Tilray Inc. was up 1.8% and Aphria Inc. was up 1.4%. Aurora Cannabis Inc. was up 2.1%, and Green Organic Dutchman Holdings was up 4.1%. The ETFMG Alternative Harvest ETF (MJ) was up 0.6% and the Horizons Mariujana Life Sciences ETF was up 1%. The S&P 500 was down 1.4% and the Dow Jones Industrial Average was down 1.7%.

-Ciara Linnane; 415-439-6400; AskNewswires@dowjones.com

(END) Dow Jones Newswires

November 20, 2018 11:29 ET (16:29 GMT)

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