Magenta Therapeutics Inc
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Health Care : Biotechnology | Company profile

Magenta Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is developing therapeutics to transform hematopoietic stem cell transplants for patients with immune and blood-based diseases. It maintains a platform with integrated and modular approach, which aims to reboot the blood and immune systems. The Company’s products include MGTA-145, MGTA-456, E478, and G100. The Company also developing a pipeline of small molecules; biologics, including antibody drug conjugates; and a cell therapy, which transplant options for many more patients with autoimmune diseases, blood cancers and genetic diseases. The Company’s C100 program targets HSCs, immune cells, and disease-causing cells, the C200 program targets HSCs and disease-causing cells and the C300 program targets only immune cells. This is achieved by tuning the antibodies to specific cellular markers or receptors that are expressed on the particular cell types.

Price
Delayed
$17.60
Day's Change
-0.23 (-1.29%)
Bid
--
Ask
--
B/A Size
--
Day's High
17.99
Day's Low
16.95
Volume
(Light)

Today's volume of 180,434 shares is on pace to be much lighter than MGTA's 10-day average volume of 396,664 shares.

180,434

UPDATE: Powell party pooper: Here are the worst-performing stocks after the Fed wrecks the market

6:48 am ET December 20, 2018 (MarketWatch)
Print

UPDATE: Powell party pooper: Here are the worst-performing stocks after the Fed wrecks the market

By Philip van Doorn, MarketWatch

The Dow Jones Industrial Average swung from a gain of as much as 1.6% to end with a decline of 1.5%

Investors crave certainty, and Federal Reserve Chairman Jerome Powell outlined the central bank's expected tightening path for interest rates Wednesday.

But the Fed's widely expected increase of the federal funds rate helped turn what started as a positive day for the stock market into a day of big declines.

The Federal Open Market Committee raised its target range for the federal funds rate (http://www.marketwatch.com/story/defying-trump-fed-hikes-interest-rates-by-a-quarter-point-2018-12-19) by a quarter point to 2.25% to 2.50%.

Read:Text of FOMC statement for December (http://www.marketwatch.com/story/text-of-fomc-statement-for-december-2018-12-19)

During a press conference (http://www.marketwatch.com/story/fed-interest-rate-decision-and-powell-press-conference-live-blog-and-video-2018-12-19), Powell indicated the Fed was likely to raise rates twice in 2019.

Here's how the stock market reversed itself Wednesday:

-- The Dow Jones Industrial Average ended with a decline of 352 points (1.5%) after being up by as much as 382 points (1.6%) before the FOMC's announcement.

-- The S&P 500 Index was up as much as 1.5% earlier on Wednesday before ending with a 1.5% decline.

-- The Nasdaq Composite Index rose as much as 1.3% on Wednesday, before the Fed's action and Powell's comments helped send it down by 2.2% at the close.

Dow losers

All but one of the 30 components of the Dow Jones Industrial Average were down Wednesday:

Company Ticker Price change - Dec. 19 Price change - December Price change - 2018 Decline from 52-week high

Intel Corp. US:INTC -4.5% -7.6% -1.3% -20.9%

Apple Inc. US:AAPL -3.1% -9.9% -4.9% -31.1%

Nike Inc. Class B US:NKE -3.1% -8.2% 10.3% -19.8%

Walgreens Boots Alliance Inc. US:WBA -2.9% -13.4% 0.9% -15.1%

Boeing Co. US:BA -2.6% -7.8% 8.4% -19.0%

3M Co. US:MMM -2.4% -8.6% -19.3% -26.9%

American Express Co. US:AXP -2.2% -12.0% -0.5% -13.8%

Johnson & Johnson US:JNJ -2.2% -13.1% -8.7% -14.3%

Cisco Systems Inc. US:CSCO -2.1% -9.9% 12.6% -12.8%

Chevron Corp. US:CVX -1.7% -9.3% -13.9% -19.5%

United Technologies Corp. US:UTX -1.7% -6.6% -10.8% -21.1%

Exxon Mobil Corp. US:XOM -1.7% -11.0% -15.4% -20.7%

Caterpillar Inc. US:CAT -1.6% -9.8% -22.4% -29.4%

Home Depot Inc. US:HD -1.5% -7.1% -11.6% -22.2%

Goldman Sachs Group Inc. US:GS -1.3% -11.2% -33.6% -38.5%

JPMorgan Chase & Co. US:JPM -1.3% -12.5% -9.0% -18.5%

Visa Inc. Class A US:V -1.1% -7.4% 15.1% -13.4%

UnitedHealth Group Inc. US:UNH -1.1% -11.0% 13.5% -13.1%

Pfizer Inc. US:PFE -1.0% -9.2% 15.9% -9.7%

Coca-Cola Co. US:KO -0.9% -5.0% 4.4% -5.8%

Procter & Gamble Co. US:PG -0.8% -2.9% -0.1% -5.3%

Merck & Co. US:MRK -0.8% -7.0% 31.1% -8.0%

Walmart Inc. US:WMT -0.6% -7.3% -8.3% -17.7%

McDonald's Corp. US:MCD -0.3% -5.0% 4.1% -6.1%

Microsoft Corp. US:MSFT -0.3% -6.5% 21.2% -10.8%

DowDuPont Inc. US:DWDP -0.2% -9.8% -26.8% -32.3%

Walt Disney Co. US:DIS -0.2% -5.4% 1.6% -9.1%

International Business Machines Corp. US:IBM -0.2% -6.3% -24.1% -32.0%

Travelers Cos. US:TRV -0.1% -8.6% -12.1% -20.9%

Verizon Communications Inc. US:VZ 0.4% -7.4% 5.5% -9.3%

Source: FactSet

You can click on the tickers for more about each company, including news, profiles, charts, estimates, price ratios and ratings.

The right-most column shows how much the shares were down from their 52-week intraday highs (adjusted by FactSet for any splits or spin-offs). A bear market is typically defined as a decline of 20% or more from a high. So it's reasonable to say that a dozen of the Dow 30 are now in bear markets, led by Goldman Sachs (GS).

S&P 500 losers

Here are Wednesday's worst-performing components of the S&P 500 Index:

Company Ticker Price change - Dec. 19 Price change - December Price change - 2018 Decline from 52-week high

FedEx Corp. US:FDX -12.2% -29.0% -34.9% -40.8%

Micron Technology Inc. US:MU -7.9% -18.5% -23.6% -51.4%

Facebook Inc. Class A US:FB -7.2% -5.2% -24.5% -39.0%

Allergan PLC US:AGN -7.0% -12.8% -16.5% -30.7%

Advanced Micro Devices Inc. US:AMD -6.9% -14.7% 76.7% -46.8%

Helmerich & Payne Inc. US:HP -6.8% -16.2% -21.5% -32.3%

L Brands Inc. US:LB -6.1% -17.8% -54.8% -56.8%

Newmont Mining Corp. US:NEM -6.1% -0.8% -14.5% -23.7%

Nvidia Corp. US:NVDA -5.7% -15.2% -28.4% -52.7%

Western Digital Corp. US:WDC -5.5% -19.4% -54.0% -65.8%

Source: FactSet

All of the day's 10 worst-performing S&P 500 stocks are in bear markets.

FedEx (FDX) was the worst performer among the S&P 500 on Wednesday, after CEO Frederick Smith said during a conference call with analysts that fears of a threat to the company's business from Amazon.com's (AMZN) Amazon Air service were "fantastical (http://www.marketwatch.com/story/fedex-ceo-its-fantastical-to-think-amazon-air-is-a-threat-2018-12-19)." He cut the company's profit forecast and gave a wide-ranging list of problems in the global economy.

Nasdaq 100 losers

Here are Wednesday's 10 worst performers among the Nasdaq 100 :

Company Ticker Price change - Dec. 19 Price change - December Price change - 2018 Decline from 52-week high

Micron Technology Inc. US:MU -7.9% -18.5% -23.6% -51.4%

NXP Semiconductors NV US:NXPI -7.4% -14.5% -39.1% -43.4%

Facebook Inc. Class A US:FB -7.2% -5.2% -24.5% -39.0%

Nvidia Corp. US:NVDA -5.7% -15.2% -28.4% -52.7%

Western Digital Corp. US:WDC -5.5% -19.4% -54.0% -65.8%

Applied Materials Inc. US:AMAT -5.3% -15.4% -38.3% -49.5%

Maxim Integrated Products Inc. US:MXIM -5.2% -11.7% -5.6% -34.1%

(MORE TO FOLLOW) Dow Jones Newswires

December 20, 2018 06:48 ET (11:48 GMT)

Copyright (c) 2018 Dow Jones & Company, Inc.

MW UPDATE: Powell party pooper: Here are the -2-

Analog Devices Inc. US:ADI -5.0% -9.0% -6.0% -19.2%

Lam Research Corp. US:LRCX -4.9% -16.5% -28.8% -44.2%

Microchip Technology Inc. US:MCHP -4.9% -8.5% -21.9% -34.2%

Source: FactSet

All but one of the day's 10 worst-performing Nasdaq 100 stocks are in a bear market.

Shares of Micron (MU) fell 7.9% as analysts worried about the semiconductor manufacturer's forecasts for 2019 (http://www.marketwatch.com/story/micron-stock-falls-amid-concerns-of-a-tough-road-ahead-2018-12-19).

Don't miss: More than half of S&P 500 stocks are now in a bear market (http://www.marketwatch.com/story/more-than-half-of-sp-500-stocks-are-now-in-a-bear-market-2018-12-17)

Create an email alert for Philip van Doorn's Deep Dive columns here (http://www.marketwatch.com/tools/alerts/newsColumn.asp).

-Philip van Doorn; 415-439-6400; AskNewswires@dowjones.com

(END) Dow Jones Newswires

December 20, 2018 06:48 ET (11:48 GMT)

Copyright (c) 2018 Dow Jones & Company, Inc.

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