Lands End Inc
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Consumer Discretionary : Internet & Direct Marketing Retail | Small Cap Growth
Company profile

Lands' End, Inc. (Lands' End) is a multi-channel retailer of casual clothing, accessories and footwear, as well as home products. The Company operates through two segments: Direct and Retail. The Company offers products through catalogs, online at The Direct segment sells products through the Company's e-commerce Websites, international Websites and direct mail catalogs. The Retail segment sells products and services through Lands' End Shops at Sears across the United States, the Company's standalone Lands' End Inlet stores and international shop-in-shops. The Company's product categories include Apparel and Non-apparel. The Non-apparel category offers accessories, footwear and home goods. The Company provides embroidery, monogramming, gift wrapping, shipping and other services. In addition, the Company offers sheets and pillowcases, duvet covers and comforters, blankets and throws, mattress pads, towels, rugs and mats, school uniforms and shower curtains.

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UPDATE: Moderna's stock closes at record high after 'compelling' early data for its coronavirus vaccine candidate

7:17 am ET May 19, 2020 (MarketWatch)

By Jaimy Lee

The company also on Monday announced that it plans to sell $1.34 billion of its stock to help fund manufacturing costs associated with the experimental COVID-19 vaccine

The people who were given Moderna Inc.'s (MRNA) coronavirus vaccine candidate in a Phase 1 clinical trial developed neutralizing antibodies, a promising finding that has propelled the vaccine into the next phase of clinical testing.

Shares of Moderna soared 25% in trading on Monday afternoon. The preclinical company's stock has gained 241% since the start of the year; it was one of the first companies to announce plans to develop a vaccine, doing so on Jan. 23, and its mRNA candidate is widely viewed as a front-runner in the effort to develop the first vaccine for the virus. It is now the first company to announce clinical findings of a vaccine that has been tested in humans.

After the stock closed at record high ( on Monday, the company announced it will sell $1.34 billion of its stock, to help fund the manufacturing of mRNA-1273. It priced the offering of 17.6 million shares of common stock at $76.00 per share.

"These interim Phase 1 data, while early, demonstrate that vaccination with mRNA-1273 elicits an immune response of the magnitude caused by natural infection," Moderna chief medical officer Dr. Tal Zaks said in a news release.

Read: These 23 companies are working on coronavirus treatments or vaccines -- here's where things stand (

At the same time, the tweaks that Moderna is making to the trial design for the Phase 2 study and some of the discussion points raised during an investor call on Monday about study locations for the final clinical trial underscore the unique challenges facing all manufacturers developing coronavirus vaccines during the pandemic.

In the topline interim trial results ( released Monday, Moderna said that eight participants taking two of the three lower dosing levels reported the same or higher level of neutralizing antibodies as in blood samples gathered by patients who have recovered from COVID-19. There were four adverse events during the trial, including one participant who reported a severe skin reaction where the investigational vaccine was administered. Three of the adverse events took place in people receiving the highest dose of the vaccine.

"While samples are not yet available for remaining participants, and we lack specifics on the exact levels of binding antibodies, we view this data as demonstrative of early signs of efficacy," Goldman Sachs analysts wrote in a note to investors. Maxim Group's Jason McCarthy described the data as "compelling."

The trial is being conducted with the National Institute of Allergy and Infectious Diseases, and the company has received at least $483 million in federal funding for its vaccine candidate this year.

Going forward, the Phase 2 trial, which Moderna said has been approved by the Food and Drug Administration to begin "shortly," will have two dosing levels (50 microgram and 100 microgram), bypassing a third dosing level (250 microgram) that was included in the first phase of testing. It plans to enroll 600 participants and is expected to begin this quarter. Moderna executives told analysts that they believe the dosing level that will make into the Phase 3 trial will be between 25 micrograms and 100 micrograms.

In the Goldman note, analysts noted that "the lower doses bode well for manufacturing capacity," a reason that many manufacturers are relying on adjuvant technology platforms marketed by GlaxoSmithKline (GSK.LN) that helps limit the amount of vaccine needed per dose.

See also:Dow soars almost 4% main stock-market indexes turn positive for May on coronavirus vaccine hope (

Moderna also said Monday that it expects a Phase 3 trial to begin in July, if the vaccine is successful in the mid-stage trial. However, one concern raised by analysts during a call on Monday focuses on whether there will be enough people with the disease in the regions where Moderna plans to conduct the late-stage trial.

"The trial needs to be run in areas where there is still sufficient virus circulating in the general population," McCarthy wrote. This is because there needs to be observed development of neutralizing antibodies. The safety is already there so far but if there is not enough virus out there to run the right trial, it could be problematic (for all the vaccine developers)."

However, Zaks expects the late-stage portion of testing to enroll people who are at higher risk of contracting the virus, he said Monday. "We will enroll people at risk both based on their age, based on their co-morbidities and based on their occupations and other sort of parameters that put people at risk," he said, according to a FactSet transcript of the call.

-Jaimy Lee; 415-439-6400;

(END) Dow Jones Newswires

May 19, 2020 07:17 ET (11:17 GMT)

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