Aeglea Bio Therapeutics Inc
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Health Care : Biotechnology |
Company profile

Aeglea BioTherapeutics, Inc. is a clinical-stage biotechnology company. The Company is focused on developing human enzyme therapeutics to benefit people with rare metabolic diseases. The Company’s product candidates include pegzilarginase and AGLE-177. The Company's lead product candidate, pegzilarginase, is a recombinant human arginase one that enzymatically degrades the amino acid arginine to lower arginine levels in patients with Arginase one Deficiency. Its engineered pegzilarginase with modifications that enhance the stability and arginine-degrading activity of the enzyme in human plasma. The Company is evaluating Pegzilarginase in a global pivotal Phase III PEACE (Pegzilarginase Effect on Arginase one Deficiency Clinical Endpoints) trial and in a Phase II open-label extension study for patients with Arginase One Deficiency. Its AGLE-177, is a novel PEGylated, or polyethylene glycol modified, human enzyme engineered to reduce Homocystinuria.

Closing Price
$6.00
Day's Change
-0.17 (-2.76%)
Bid
--
Ask
--
B/A Size
--
Day's High
6.21
Day's Low
5.90
Volume
(Average)
Volume:
157,454

10-day average volume:
174,612
157,454

Salesforce.com Inc., American Express Share Gains Contribute To Dow's 511-point Rally

3:52 pm ET September 23, 2021 (MarketWatch)
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This article was automatically generated by MarketWatch using technology from Automated Insights.

Shares of Salesforce.com Inc. and American Express are posting strong returns Thursday afternoon, propelling the Dow Jones Industrial Average rally. The Dow DJIA is trading 511 points, or 1.5%, higher, as shares of Salesforce.com Inc. CRM and American Express AXP are contributing to the index's intraday rally. Salesforce.com Inc.'s shares have risen $18.58 (7.2%) while those of American Express have gained $5.92, or 3.5%, combining for an approximately 161-point boost for the Dow. Also contributing significantly to the gain are JPMorgan Chase JPM, Caterpillar CAT, and Visa V. A $1 move in any of the benchmark's 30 components results in a 6.58-point swing.

Data source: Dow Jones Market Data, FactSet. Data compiled September 23, 2021.

-MarketWatch Automation

	

(END) Dow Jones Newswires

September 23, 2021 15:52 ET (19:52 GMT)

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