Aeglea Bio Therapeutics Inc
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Health Care : Biotechnology |
Company profile

Aeglea BioTherapeutics, Inc. is a clinical-stage biotechnology company. The Company is focused on developing human enzyme therapeutics to benefit people with rare metabolic diseases. The Company’s product candidates include pegzilarginase and AGLE-177. The Company's lead product candidate, pegzilarginase, is a recombinant human arginase one that enzymatically degrades the amino acid arginine to lower arginine levels in patients with Arginase one Deficiency. Its engineered pegzilarginase with modifications that enhance the stability and arginine-degrading activity of the enzyme in human plasma. The Company is evaluating Pegzilarginase in a global pivotal Phase III PEACE (Pegzilarginase Effect on Arginase one Deficiency Clinical Endpoints) trial and in a Phase II open-label extension study for patients with Arginase One Deficiency. Its AGLE-177, is a novel PEGylated, or polyethylene glycol modified, human enzyme engineered to reduce Homocystinuria.

Closing Price
$6.00
Day's Change
-0.17 (-2.76%)
Bid
--
Ask
--
B/A Size
--
Day's High
6.21
Day's Low
5.90
Volume
(Average)
Volume:
157,454

10-day average volume:
174,612
157,454

Walgreens Boots, Home Depot Share Losses Contribute To Dow's 332-point Fall

2:01 pm ET September 30, 2021 (MarketWatch)
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This article was automatically generated by MarketWatch using technology from Automated Insights.

Behind losses for shares of Walgreens Boots and Home Depot, the Dow Jones Industrial Average is falling Thursday afternoon. Shares of Walgreens Boots WBA and Home Depot HD have contributed to the blue-chip gauge's intraday decline, as the Dow DJIA was most recently trading 332 points lower (-1.0%). Walgreens Boots's shares have dropped $1.34 (2.7%) while those of Home Depot are down $7.34, or 2.2%, combining for a roughly 57-point drag on the Dow. Also contributing significantly to the decline are 3M MMM, Caterpillar CAT, and UnitedHealth UNH. A $1 move in any of the Dow's 30 components results in a 6.58-point swing.

Data source: Dow Jones Market Data, FactSet. Data compiled September 30, 2021.

-MarketWatch Automation

	

(END) Dow Jones Newswires

September 30, 2021 14:01 ET (18:01 GMT)

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