Aeglea Bio Therapeutics Inc
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Health Care : Biotechnology |
Company profile

Aeglea BioTherapeutics, Inc. is a clinical-stage biotechnology company. The Company is focused on developing human enzyme therapeutics to benefit people with rare metabolic diseases. The Company’s product candidates include pegzilarginase and AGLE-177. The Company's lead product candidate, pegzilarginase, is a recombinant human arginase one that enzymatically degrades the amino acid arginine to lower arginine levels in patients with Arginase one Deficiency. Its engineered pegzilarginase with modifications that enhance the stability and arginine-degrading activity of the enzyme in human plasma. The Company is evaluating Pegzilarginase in a global pivotal Phase III PEACE (Pegzilarginase Effect on Arginase one Deficiency Clinical Endpoints) trial and in a Phase II open-label extension study for patients with Arginase One Deficiency. Its AGLE-177, is a novel PEGylated, or polyethylene glycol modified, human enzyme engineered to reduce Homocystinuria.

Closing Price
$6.00
Day's Change
-0.17 (-2.76%)
Bid
--
Ask
--
B/A Size
--
Day's High
6.21
Day's Low
5.90
Volume
(Average)
Volume:
157,454

10-day average volume:
174,612
157,454

UnitedHealth, Caterpillar Share Gains Lead Dow's 368-point Rally

9:46 am ET October 14, 2021 (MarketWatch)
Print

This article was automatically generated by MarketWatch using technology from Automated Insights.

Shares of UnitedHealth and Caterpillar are seeing strong returns Thursday morning, propelling the Dow Jones Industrial Average rally. The Dow DJIA was most recently trading 368 points, or 1.1%, higher, as shares of UnitedHealth UNH and Caterpillar CAT have contributed to the index's intraday rally. UnitedHealth's shares are up $25.77 (6.4%) while those of Caterpillar have gained $4.33 (2.3%), combining for an approximately 198-point boost for the Dow. American Express AXP, Intel INTC, and Walt Disney DIS are also contributing significantly to the gain. A $1 move in any of the index's 30 components results in a 6.58-point swing.

Data source: Dow Jones Market Data, FactSet. Data compiled October 14, 2021.

-MarketWatch Automation

	

(END) Dow Jones Newswires

October 14, 2021 09:46 ET (13:46 GMT)

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