Sierra Oncology Inc
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Health Care : Biotechnology | Small Cap Value
Based in Canada
Company profile

Sierra Oncology, Inc. is late stage drug development company. The Company is focused on advancing targeted therapeutics for the treatment of patients with unmet medical needs in hematology and oncology. Momelotinib, the Company’s lead drug candidate, is a potent, selective and orally-bioavailable janus kinase one (JAK1), janus kinase two (JAK2) and activin a receptor type one (ACVR1) inhibitor with a differentiated therapeutic profile in myelofibrosis. The Company is also developing a portfolio of deoxyribonucleic acid (DNA) damage response (DDR) assets, consisting of SRA737 and SRA141. SRA737 is a potent, selective, orally bioavailable small molecule inhibitor of checkpoint kinase 1 (Chk1), a key regulator of cell cycle progression and the DDR network. SRA141 is a potent, selective, orally bioavailable small molecule inhibitor of Cell division cycle 7 kinase (Cdc7).

Day's Change
0.04 (0.07%)
B/A Size
Day's High
Day's Low

Today's volume of 19,422 shares is on pace to be much lighter than SRRA's 10-day average volume of 251,849 shares.


American Airlines Group Inc. Stock Falls Monday, Underperforms Market

4:32 pm ET January 10, 2022 (MarketWatch)

This article was automatically generated by MarketWatch using technology from Automated Insights.

Shares of American Airlines Group Inc. (AAL) slid 2.54% to $18.79 Monday, on what proved to be an all-around poor trading session for the stock market, with the S&P 500 Index falling 0.14% to 4,670.29 and Dow Jones Industrial Average falling 0.45% to 36,068.87. American Airlines Group Inc. closed $7.30 short of its 52-week high ($26.09), which the company achieved on March 18th.

The stock underperformed when compared to some of its competitors Monday, as Southwest Airlines Co. (LUV) fell 0.24% to $45.24, Delta Air Lines Inc. (DAL) fell 2.12% to $40.63, and United Airlines Holdings Inc. (UAL) fell 1.54% to $46.58. Trading volume (25.4 M) remained 10.7 million below its 50-day average volume of 36.1 M.

Data source: Dow Jones Market Data, FactSet. Data compiled Janurary 10, 2022.

-MarketWatch Automation


(END) Dow Jones Newswires

January 10, 2022 16:32 ET (21:32 GMT)

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