Xilio Therapeutics Inc
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Company profile

Xilio Therapeutics, Inc. is a biotechnology company. The Company is focused on harnessing the immune system to achieve clinical responses for cancer patients. It offers a geographically precise solutions (GPS) platform to engineer molecules, including cytokines and other biologics, that are designed to enhance therapeutic index. Using its GPS platform, the Company is engaged in developing a pipeline of tumor-selective cytokine and checkpoint inhibitor immunotherapies to treat cancer. Its product candidates include XTX101, XTX202, XTX301, and XTX401. XTX101 is a clinical-stage, tumor-selective anti-cytotoxic T-lymphocyte-associated protein (CTLA-4), monoclonal antibody (mAb), which is designed to improve upon the therapeutic index of existing anti-CTLA-4 therapies. XTX202 and XTX301 are an engineered form of interleukin 2 (IL-2) that is masked with a protein domain to prevent binding activity until the protein domain is cleaved off by tumor microenvironment (TME)-associated proteases.

Closing Price
Day's Change
-0.01 (-0.42%)
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(Heavy Day)

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Warren Buffett: Berkshire quickly bought big stake in Occidental Petroleum in a 'casino' market

12:15 pm ET April 30, 2022 (MarketWatch)

Berkshire Hathaway (BRKA) was able to quickly buy a large stake in Occidental Petroleum Corp.(OXY) during the first quarter as the market has been "a casino" to an "extraordinary degree" over the past couple years, said Berkshire chief executive officer Warren Buffett at the conglomerate's annual meeting in Omaha on Saturday. He said Berkshire bought a 14% stake in about two weeks. "I find that just incredible," said Buffett. "You wouldn't be able to do that with Berkshire." Buffett said that "overwhelmingly," large U.S. companies have become "poker chips," with people buying and selling call options as opposed to making investments. He said the "gambling" nature of the stock market enabled Berkshire to quickly buy 14% of "a business that's been around for decades," Buffett said.

-Christine Idzelis


(END) Dow Jones Newswires

April 30, 2022 12:15 ET (16:15 GMT)

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