Cyclo Therapeutics Equity Warrants Exp 14th Nov 2025 *W EXP 12/11/2025
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Health Care : Biotechnology | Small Cap Value
Company profile

Cyclo Therapeutics, Inc. is a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease. The Company's lead drug candidate, Trappsol Cyclo (hydroxypropyl beta cyclodextrin) is for the treatment of Niemann-Pick Type C disease (NPC). NPC is a rare and fatal cholesterol metabolism disease that impacts the brain, lungs, liver, spleen, and other organs. It is also focusing on the use of cyclodextrins in the treatment of Alzheimer's disease. The Company's product lines include Trappsol and Aquaplex. It sells its chemical products directly to customers in the pharmaceutical, diagnostics, and industrial chemical industries, and to chemical supply distributors. The Company also sells cyclodextrins and related products to the pharmaceutical, nutritional, and other industries, primarily for use in diagnostics and specialty drugs.

Closing Price
$0.76
Day's Change
0.00 (0.00%)
Bid
--
Ask
--
B/A Size
--
Day's High
0.78
Day's Low
0.5088
Volume
(Above Average)
Volume:
1,592

10-day average volume:
1,592
1,592

These 19 large-cap stocks have now dropped at least 60% from their 52-week highs

1:15 pm ET June 11, 2022 (MarketWatch)
Print

By Philip van Doorn

The biggest losers in the stock market include DocuSign, PayPal, Netflix and Zoom Video Communications

The latest inflation figures on June 10 were worse than expected and the effect on stock prices was brutal. A list of stocks in the S&P 500 and the Nasdaq-100 Index that have fallen at least 60% from 52-week highs is below.

The consumer-price index report for May from the Bureau of Labor Statistics came in much worse than expected, with a 1% increase in prices during the month and a year-over-year CPI increase of 8.6% -- a new 40-year record.

Hand-in-hand with the inflation report was a record-low figure for the University of Michigan's Consumer Sentiment Index.

Weak consumer sentiment points to the weakest stock sector

Here's a summary of performance for the 11 sectors of the S&P 500 and other broad indexes, as of 11:40 a.m. ET on June 10:

Index                         Price change -- June 10  Price change -- 2022  Decline from 52-week intraday high  Date of 52-week intraday high 
Consumer Discretionary                         -4.3%                 -30%                                -33%           11/19/2021 
Information Technology                         -3.7%                 -25%                                -26%           12/27/2021 
Financials                                     -3.6%                 -17%                                -22%           01/12/2022 
Materials                                      -3.1%                 -10%                                -10%           12/31/2021 
Communication Services                         -3.0%                 -28%                                -33%           09/01/2021 
Industrials                                    -3.0%                 -14%                                -15%           01/04/2022 
Energy                                         -2.4%                  57%                                 -5%           06/08/2022 
Real Estate                                    -1.8%                 -20%                                -20%           12/31/2021 
Health Care                                    -1.7%                 -11%                                -12%           04/08/2022 
Utilities                                      -0.8%                  -1%                                 -8%           04/08/2022 
Consumer Staples                               -0.4%                  -7%                                -12%           04/20/2022 
S&P 500                                        -2.9%                 -18%                                -19%           01/04/2022 
Dow Jones Industrial Average                   -2.5%                 -13%                                -15%           01/05/2022 
Nasdaq Composite Index                         -3.6%                 -28%                                -30%           11/22/2021 
Nasdaq-100 Index                               -3.6%                 -28%                                -29%           11/22/2021 
                                                                                                                             Source: FactSet 

All 11 sectors of the S&P 500 were down for the day.

The only sector with a positive return in 2022 has been energy, with a 57% gain as the price of West Texas Crude Oil has risen 59%, based on continuous forward-month prices compiled by FactSet.

Stocks down at least 60% from their 52-week highs

To take a broader look at large companies suffering the biggest share price declines, we added the components of the Nasdaq-100 Index to the S&P 500 for a list of 519 companies after removing duplicates. (The Nasdaq-100 includes the largest 100 nonfinancial companies, by market capitalization, in the full Nasdaq Composite Index .)

Within that enlarged group, these 19 stocks have dropped at least 60% from their 52-week highs:

Company                                 Ticker  Price change -- June 10  Price change -- 2022  Decline from 52-week high  Date of 52-week intraday high 
DocuSign Inc.                            DOCU                   -24.6%               -56.8%                       -79%           08/10/2021 
Etsy Inc.                                ETSY                    -8.2%               -65.2%                       -75%           11/26/2021 
Moderna Inc.                             MRNA                    -5.9%               -50.4%                       -75%           08/10/2021 
PayPal Holdings Inc.                     PYPL                    -6.3%               -58.2%                       -75%           07/26/2021 
Netflix Inc.                             NFLX                    -4.7%               -69.5%                       -74%           11/17/2021 
Zoom Video Communications Inc. Class A    ZM                     -2.5%               -41.5%                       -74%           07/07/2021 
Lucid Group Inc.                         LCID                    -4.2%               -52.5%                       -69%           11/17/2021 
Okta Inc. Class A                        OKTA                    -5.9%               -60.2%                       -68%           09/03/2021 
Align Technology Inc.                    ALGN                    -3.5%               -61.4%                       -66%           09/23/2021 
MercadoLibre Inc.                        MELI                    -7.4%               -48.6%                       -65%           09/02/2021 
Carnival Corp.                           CCL                     -5.4%               -44.9%                       -65%           06/09/2021 
Under Armour Inc. Class A                UAA                     -4.1%               -52.4%                       -63%           11/19/2021 
Penn National Gaming Inc.                PENN                    -5.4%               -38.1%                       -63%           09/08/2021 
Atlassian Corp. PLC Class A              TEAM                    -7.1%               -52.3%                       -62%           10/29/2021 
Caesars Entertainment Inc.               CZR                     -8.1%               -50.7%                       -62%           10/01/2021 
Illumina Inc.                            ILMN                    -9.6%               -46.6%                       -61%           08/16/2021 
Norwegian Cruise Line Holdings Ltd.      NCLH                    -4.5%               -36.7%                       -61%           06/09/2021 
Zscaler Inc.                              ZS                     -5.6%               -52.9%                       -60%           11/19/2021 
Ceridian HCM Holding Inc.                 CD                     -4.6%               -49.7%                       -60%           11/03/2021 
 

Click on the tickers for more about each company.

Then read Tomi Kilgore's detailed guide to the wealth of information for free on the MarketWatch quote page.

The stock that was down the most from its 52-week high was DocuSign Inc. (DOCU), also the worst performer on June 10 after the company lowered its billings outlook. Analysts then downgraded the stock.

-Philip van Doorn

	

(END) Dow Jones Newswires

June 11, 2022 13:15 ET (17:15 GMT)

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