Apellis Pharmaceuticals Inc
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Health Care : Biotechnology | Small Cap Growth
Company profile

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company that is focused on developing therapeutic compounds to treat disease through the inhibition of the complement system. The Company is developing pegcetacoplan with Sobi for systemic administration in several indications, including paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy, immune complex membranoproliferative glomerulonephritis, amyotrophic lateral sclerosis, cold agglutinin disease, and hematopoietic stem cell transplantation thrombotic microangiopathy. The Company's advanced clinical programs targeting component 3 with Phase III clinical trials of its lead product candidate, pegcetacoplan, in multiple indications. Pegcetacoplan is a conjugate of a compstatin analogue, formulated both for ophthalmological administration by injections directly into the eye, and systemic administration by subcutaneous injection, which is an injection into the tissue under the skin.

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E.l.f. and Lowe's named best holiday ideas at D.A. Davidson with analyst upbeat on overall holiday season

8:06 am ET November 28, 2022 (MarketWatch)

D.A. Davidson named E.l.f. Beauty Inc. stock as its best holiday idea in health & beauty/leisure on Monday and home-improvement retailer Lowe's as best idea in retailing broadlines & hardlines in an upbeat note predicting solid holiday sales growth this year. Reports suggest Black Friday weekend sales were up solidly versus last year, while Mastercard's SpendingPulse said spending rose 12% on a relatively even split between in-store and online, analysts led by Linda Bolton Weiser wrote in a note. Sensormatics Solutions found in-store traffic was up 2.9% on Black Friday and up 19.7% on Thanksgiving Day. "These checks are consistent with our admittedly unscientific store checks which showed nice levels of traffic at stores. But, perhaps most importantly, our data work shows that retailers are having some success working down their inventory glut," the analysts wrote in a note to clients. E.l.f. is expected to post another upside surprise for its fiscal third quarter, said the note. That's because it is de-emphasizing holiday gift sets, which dampen gross margins; its point-of-sale growth in the first two months of the quarter stands at about 39%; and management had planned a big boost in marketing spending which should drive consumption in the quarter. Lowe's, meanwhile, "usually performs well this time of the year, due in large part to relatively low holiday exposure / risk," said the note. E.l.f. shares were up 0.9% premarket and have gained 67% in the year to date. Lowe's was not active but is down 18% in the year to date, while the S&P 500 has fallen 15%.

-Ciara Linnane


(END) Dow Jones Newswires

November 28, 2022 08:06 ET (13:06 GMT)

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