Tempest Therapeutics Inc
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Health Care : Biotechnology |
Company profile

Tempest Therapeutics, Inc. (Tempest) is a clinical-stage oncology company. The Company is focused on developing small molecules that combine both tumor-targeted and immune-mediated mechanisms with the potential to treat a range of tumors. The Company’s two clinical programs include TPST-1120 and TPST-1495. TPST-1120 is a selective antagonist of peroxisome proliferator-activated receptor alpha (PPARa). TPST-1120 is in Phase I and II trials in solid tumors, including a global randomized Phase Ib/II trial in combination with the standard-of-care first-line regimen of atezolizumab and bevacizumab in patients with advanced or metastatic hepatocellular carcinoma (HCC). Its second clinical program, TPST-1495, a dual antagonist of the EP2 and EP4 receptors of prostaglandin E2, and is in Phase I monotherapy and combination trials in solid tumors.

Closing Price
Day's Change
-0.20 (-9.76%)
B/A Size
Day's High
Day's Low
(Heavy Day)

10-day average volume:

Bed Bath & Beyond stock falls again, has plunged more than 70% during a 12-day stretch in which it has declined 11 times

1:37 pm ET February 23, 2023 (MarketWatch)

Shares of Bed Bath & Beyond Inc. (BBBY) took a 6.8% beating Thursday, which put them on track for a third-straight loss and a seven-week closing low. The stock has shed 16.6% over the past three sessions, and plunged 74.2% amid a 12-day stretch in which it has declined 11 sessions. That stretch of weakness followed the home-goods retailer's announcement of plans to sell convertible preferred shares, in an effort to get out of a loan default and stave off bankruptcy. That announcement came after the Feb. 6 closing bell, and just after a "meme"-like 92.1% surge in the stock. The stock was headed for the lowest close since Jan. 6, which was the day it closed at a 30-year low of $1.31. Among other former and recent "meme"-stocks, AMC Entertainment Holdings Inc. shares (AMC) eased 0.2% in afternoon trading Thursday, while shares of GameStop Corp. (GME) lost 2.8% and Carvana Co. (CVNA) shed 3.6%. Meanwhile, the S&P 500 fell 0.3%.

-Tomi Kilgore


(END) Dow Jones Newswires

February 23, 2023 13:37 ET (18:37 GMT)

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