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Health Care : Biotechnology |
Company profile

Elevation Oncology, Inc. is an oncology company. The Company is focused on the discovery and development of selective cancer therapies to treat patients across a range of solid tumors with significant unmet medical needs. Its lead product candidate, EO-3021 (SYSA1801 or CPO102), is an antibody-drug conjugate (ADC) designed to target Claudin 18.2, a clinically validated molecular target, which can selectively deliver a cytotoxic payload directly to cancer cells expressing Claudin 18.2. Claudin 18.2 is expressed across several solid tumor types, including many gastrointestinal cancers such as gastric, gastroesophageal junction and pancreatic cancer. Claudin 18.2 is also expressed in ovarian cancer, non-small cell lung cancer (NSCLC) and other solid tumors. The Company is exploring opportunities through new or existing partnerships and business development opportunities to expand its novel oncology pipeline.

Day's Change
-1.14 (-40.43%)
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(Heavy Day)

Today's volume of 5,633,037 shares is on pace to be much greater than ELEV's 10-day average volume of 8,118,558 shares.


March Madness: 68 million American adults plan to bet on this year's tournament

2:48 pm ET March 16, 2023 (MarketWatch)

By Weston Blasi

Since last year's March Madness, Massachusetts, Kansas and Ohio legalized sports betting

The 2023 men's NCAA March Madness tournament will likely be one of the biggest sports betting events in U.S. history.

Americans plan to wager roughly $15.5 billion on the March Madness tournament this year, up from $3.1 billion in 2022, according to estimates from the American Gaming Association, when accounting for legal wagers at regulated sportsbooks, bracket contests and casual bets with friends.

See also: Barack Obama filled out his March Madness brackets. See his Final Four here

"March Madness is one of the best traditions in American sports -- and America's most wagered-on competition," said AGA President and CEO Bill Miller. "Critically, the expansion of regulated sports betting over the past five years has brought safeguards to more than half of American adults who can now bet legally in their home market."

In total, 68 million American adults say they plan to place at least some kind of bet on this year's tournament, compared with 45 million people who said the same in 2022. March Madness is also expected to lure more people to wager than the 2023 Super Bowl, which saw 50.4 million bettors.

The Super Bowl is consistently the most-wagered-on single event of the year. At times, NCAA's March Madness basketball tournament has seen more wagers, but it's a series of games, and not a single game.

See also: WWE exploring possibility of legal betting on scripted matches, report says

Since last year's March Madness tournament, more U.S. states have legalized online sports betting, including Massachusetts, Kansas and Ohio.

In 2018, when the U.S. Supreme Court ended the Professional and Amateur Sports Protection Act, it gave states individual legislative power to legalize sports betting. Some form of live sports wagering is legal in 33 states, plus Washington, D.C., according to the AGA

The 2023 tournament will have Las Vegas, Nev., the sports betting capital of the world, as one of the regional host locations. This marks the first time Las Vegas has hosted part of the March Madness tournament, and could create extra buzz about the games. Similarly, the 2023 Super Bowl was the first time the game was played in a state (Arizona) where betting was legal at the time of the game.

See also: 'Deadpool' star turned business mogul Ryan Reynolds is on a roll with Mint Mobile deal

Alabama, Houston, Kansas and Purdue are the top seeds in this year's tournament, with Alabama earning its first-ever No. 1 seed in the tournament in school history.

The most popular teams that bettors are choosing to wager on to win the entire tournament are Kentucky (9%), followed by Texas A&M (8%), Gonzaga, UCLA and Alabama (6%). Houston is seen as the betting favorite to win the tournament, according to DraftKings (DKNG) Sportsbook, followed by Alabama and Purdue.

The opening round of the 2023 men's March Madness tournament starts on Thursday afternoon.

Read on: LeBron James vs. Michael Jordan: who is the GOAT when it comes to net worth?

-Weston Blasi


This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.


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March 16, 2023 14:48 ET (18:48 GMT)

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