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Company profile

Xilio Therapeutics, Inc. is a biotechnology company. The Company is focused on harnessing the immune system to achieve clinical responses for cancer patients. It offers a geographically precise solutions (GPS) platform to engineer molecules, including cytokines and other biologics, that are designed to enhance therapeutic index. Using its GPS platform, the Company is engaged in developing a pipeline of tumor-selective cytokine and checkpoint inhibitor immunotherapies to treat cancer. Its product candidates include XTX101, XTX202, XTX301, and XTX401. XTX101 is a clinical-stage, tumor-selective anti-cytotoxic T-lymphocyte-associated protein (CTLA-4), monoclonal antibody (mAb), which is designed to improve upon the therapeutic index of existing anti-CTLA-4 therapies. XTX202 and XTX301 are an engineered form of interleukin 2 (IL-2) that is masked with a protein domain to prevent binding activity until the protein domain is cleaved off by tumor microenvironment (TME)-associated proteases.

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37% of Consumers Trust Social Media Influencers Over Brands

8:01 am ET May 3, 2022 (PR Newswire) Print

-- 80 percent of consumers have purchased products in direct response to social media content

-- Only 13 percent discover new products or brands via traditional TV advertising

-- 98 percent find customer service interactions frustrating

Social media influencers and online communities are reshaping how consumers form opinions, buy from brands, and get their questions answered, according to a new study from Oracle and Brent Leary, partner, CRM Essentials. The study of more than 2,000 adults, ages 18 to 80 in the United States, found that consumers, particularly Gen Z, are increasingly turning to social media influencers and online communities to make purchasing decisions and receive customer service.


The way we research, learn about, and purchase new products is changing

Consumers are turning to social media influencers for advice and recommendations with many now trusting social media influencers more than brands.

-- 37 percent consumers trust social media influencers over brands; Gen Z and Millennials are two times more likely than Boomers to trust influencers.

-- 28 percent of consumers discover new products and brands through influencers. Gen Z are the most likely to discover products and brands this way (32 percent), compared to only 13 percent of Boomers.

-- Only 13 percent discover new products or brands via traditional TV advertising. Boomers are seven times more likely than Gen Z to discover new products and brands via traditional TV advertising.

-- 44 percent turn to social media ads and 13 percent turn to influencers to inform their purchasing decisions. 84 percent of Gen Z has purchased products in direct response to social media content, compared to only 46 percent of Boomers.

-- When it comes to following influencers, YouTube is the most popular channel with 21 percent of consumers following influencers on YouTube. Gen Z favors TikTok (25 percent), followed closely by YouTube (23 percent) and Instagram (22 percent), while Boomers favor Facebook (23 percent), YouTube (15 percent) and TikTok (5 percent).

Online communities are replacing traditional customer service channels

Consumers are fed up with traditional customer service engagements and are turning to social media channels and online communities to get their questions answered.

-- 98 percent of consumers find customer service interactions frustrating and 15 percent would rather sit in traffic than engage with a brand's customer service channels.

-- Only 18 percent of consumers want to pick up the phone and call customer service when they have questions. 26 percent of Boomers want to receive service this way, compared to only 14 percent of Gen Z.

-- When submitting a service inquiry to a brand, 31 percent of consumers would prefer to comment on a brand's social media page and 24 percent would prefer to direct message a brand on social media. Gen Z is two times more likely than Boomers to want to receive customer service in this way.

-- 93 percent of consumers turn to social media platforms like YouTube and TikTok to get questions answered and get the most out of a product or service. 95 percent of Gen Z use online communities in this way compared to 79 percent of Boomers.

-- Consumers trust YouTube and TikTok videos because they are created by other consumers (20 percent), easily searchable (19 percent), illustrative (16 percent) and there are a plethora to choose from (14 percent).

Supporting Quotes

"Millennials and Gen Z create and extend relationships in a completely different way than their parents' generations did, and that impacts who they trust, and how that trust translates into basic activities like learning, shopping and relationship building," said Brent Leary, partner, CRM Essentials. "As this study shows, it's time for brands to rethink how they connect with customers outside of the traditional or controlled marketing channels. By building out a strong and authentic online presence, businesses have an opportunity to collaborate and leverage creator communities and social platforms that are equipped to provide more genuine buying and service experiences."

"I rebuilt my car during the pandemic all by watching YouTube videos. This is a testament to how empowered we all are to learn about anything we wish and at any time. And we do so by watching content made by people with similar interests," said Jeff Wartgow, vice president, Oracle. "The powerful dynamic between user generated content and today's social platforms is an opportunity for brands to reimagine experiences as younger generations, Millennials and Gen Z, increasingly have more buying power."


The survey was fielded in January 2022 to 2,072 adults ages 18 to 80 in the United States.

About Oracle

Oracle offers suites of integrated applications plus secure, autonomous infrastructure in the Oracle Cloud. For more information about Oracle (NYSE: ORCL), please visit us at oracle.com.


Oracle, Java, and MySQL are registered trademarks of Oracle Corporation.


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