Karuna Therapeutics Inc
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Health Care : Biotechnology | Small Cap Value
Company profile

Karuna Therapeutics Inc. is a clinical-stage biopharmaceutical company. The Company is focused on to create and deliver transformative medicines for people living with psychiatric and neurological conditions. Its lead product candidate, KarXT, is an oral modulator of muscarinic receptors that are located both in the central nervous system (CNS) and various peripheral tissues. It is initially developing KarXT, for the treatment of acute psychosis in patients with schizophrenia. The Company is developing a pipeline of therapeutic programs to address symptoms associated with schizophrenia and psychosis associated with Alzheimer’s disease (AD), as well as various forms of pain. KarXT is a combination of xanomeline and trospium. KarXT combines xanomeline, a muscarinic agonist, with trospium, a muscarinic antagonist, to stimulate muscarinic receptors in the CNS. It is advancing a pipeline of therapeutic programs to address the positive, negative and cognitive symptoms.

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Today's volume of 27,849 shares is on pace to be much lighter than KRTX's 10-day average volume of 191,081 shares.


Amazon's 2021 Small Business Empowerment Report Reveals Third-Party Sellers Have Created More than 1.8 Million U.S. Jobs

6:00 am ET October 19, 2021 (BusinessWire) Print

--More than 200,000 small and medium-sized businesses from around the world began selling in Amazon's U.S. store in one year

--Amazon Accelerate seller conference begins Wednesday, October 20

Amazon (NASDAQ:AMZN) today released its 2021 Small Business Empowerment Report outlining how the company provides opportunity, tools, and services to help more than 500,000 third-party selling partners in the U.S. reach hundreds of millions of customers, increase revenue and profits, and create good jobs across America. The report comes just ahead of the Amazon Accelerate 2021 virtual conference for sellers, October 20-21, which will include appearances by Amazon CEO Andy Jassy and Worldwide Consumer CEO Dave Clark. Amazon will welcome thousands of U.S. sellers to the second annual conference, which will feature new product and service announcements, seller presentations, and more than 30 sessions providing insights and strategies for current and aspiring entrepreneurs. To view the full session catalog and register to attend, visit www.AmazonAccelerate.com.

The 2021 Small Business Empowerment Report details how Amazon provides small business owners, startups, and entrepreneurs with support, tools, and opportunities to sell their products online, scale their business, build their brand, and create economic impact. Sellers have created an estimated 1.8 million U.S.-based jobs managing, operating, and supporting their Amazon-related businesses.

"Over 20 years ago, we made the decision to open our store's virtual shelves to third-party sellers. At the time, big-box retailers had been pushing small businesses out of the retail market," said Dave Clark, CEO of Amazon Worldwide Consumer. "But we made a bet that bringing selling partners into our store would not only be a win for customers who want vast product selection, low prices, and fast delivery, but it would also be a win for small businesses that want to reach more customers, increase their revenue and profits, and create good jobs. It proved to be a great bet."

The number of American sellers who surpassed $1 million in sales grew by nearly 15%. In the 12 months ending on August 31, 2021, American sellers:

Sold more than 3.8 billion products, averaging 7,400 every minute. Averaged more than $200,000 in sales, up year-over-year from about $170,000. Had nearly $2.2 billion in international export sales, up year over year from nearly $1.5 billion.

"When COVID hit, BlueZone was forced to temporarily close all of its physical stores and downsize from 75 employees to 12," said Kyle Robertson, director of marketing for BlueZone Sports. "After going all-in on Amazon in April 2020, BlueZone now has more employees and more brick-and-mortar locations than we did pre-pandemic thanks to growth on Amazon."

In the report, Amazon also revealed the top 10 states with the most sellers in Amazon's stores per capita and the top 10 states with the fastest-growing sellers selling in Amazon's stores.

The top 10 states with the most sellers per capita: Delaware with more than 2,000 sellers Florida with more than 50,000 sellers Utah with more than 7,500 sellers California with more than 88,000 sellers Wyoming with more than 1,000 sellers New Jersey with more than 20,000 sellers Nevada with more than 6,500 sellers New York with more than 40,000 sellers Colorado with more than 10,000 sellers Washington with more than 13,000 sellers The top 10 states with the most year-over-year sales growth for sellers: Nebraska with 60% growth South Dakota with 40% growth Delaware with 35% growth Iowa with 33% growth Kansas with 32% growth Washington with 29% growth West Virginia with 28% growth Arizona with 27% growth South Carolina with 27% growth Connecticut with 25% growth

In 2020, Amazon invested more than $18 billion in selling partner success to help sellers quickly launch their businesses in Amazon's store, scale and reach more customers, and build their brands. That investment includes launching new tools and services, and the more than 24,000 employees focused on supporting sellers across the company.

To learn more about small and medium-sized businesses working with Amazon, and to view the full 2021 Amazon Small Business Empowerment Report, visit aboutamazon.com/smallbusiness.

About Amazon Amazon is guided by four principles: customer obsession rather than competitor focus, passion for invention, commitment to operational excellence, and long-term thinking. Amazon strives to be Earth's Most Customer-Centric Company, Earth's Best Employer, and Earth's Safest Place to Work. Customer reviews, 1-Click shopping, personalized recommendations, Prime, Fulfillment by Amazon, AWS, Kindle Direct Publishing, Kindle, Career Choice, Fire tablets, Fire TV, Amazon Echo, Alexa, Just Walk Out technology, Amazon Studios, and The Climate Pledge are some of the things pioneered by Amazon. For more information, visit amazon.com/about and follow @AmazonNews.

View source version on businesswire.com: https://www.businesswire.com/news/home/20211019005485/en/

SOURCE: Amazon.com, Inc.">

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