Rain Oncology Inc
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Health Care : Pharmaceuticals |
Company profile

Rain Oncology Inc. is a late-stage precision oncology company. The Company is focused on developing therapies that target oncogenic drivers to genetically select patients. Its product candidate includes milademetan. Milademetan is an oral, small molecule inhibitor of the p53-mouse double minute 2 (p53-MDM2) complex that reactivates p53. The product candidate is being developed in patients with MDM2-dependent cancers. p53 acts as a regulator of various cellular processes. The activity of p53 is controlled and regulated by the inhibitory protein MDM2. MDM2 binds to p53, thereby inducing degradation and allowing normal cells to function properly. Milademetan, by binding MDM2 at the p53 interaction site, prevents the formation of the MDM2-p53 complex, allowing p53 reactivation and subsequent transcription of genes that trigger cancer cell cycle arrest or apoptosis and can be readily measured by increases in the pharmacodynamic marker MIC-1 (GDF15) in the blood.

Closing Price
$1.23
Day's Change
-0.06 (-4.65%)
Bid
--
Ask
--
B/A Size
--
Day's High
1.32
Day's Low
1.21
Volume
(Light)
Volume:
1,239,101

10-day average volume:
2,902,462
1,239,101

Rain Oncology Announces Oral Presentation at the 2023 ESMO Sarcoma and Rare Cancers Annual Congress

5:50 am ET March 21, 2023 (Globe Newswire) Print
Rain Oncology Announces Oral Presentation at the 2023 ESMO Sarcoma and Rare Cancers Annual CongressGlobeNewswireMarch 21, 2023

NEWARK, Calif., March 21, 2023 (GLOBE NEWSWIRE) -- Rain Oncology Inc. (NasdaqGS: RAIN), ("Rain"), a late-stage company developing precision oncology therapeutics with its lead product candidate, milademetan, an oral, small molecule inhibitor of the MDM2-p53 complex that reactivates p53, today announced an abstract accepted as a proffered paper presentation at the 2023 ESMO Sarcoma and Rare Cancers Annual Congress in Lugano, Switzerland.

Presentation Title:MDM2 inhibitor milademetan: safety profile and management of adverse events (AEs)
Presentation Number:43O
Presenter:Chiara Fabbroni, MD, National Cancer Institute, Milan, Italy
Session Date and Time:Tuesday, March 21, 2023, 10:50am-12:10pm Central European Time
Location:Hall A

A copy of the presentation materials can be accessed by visiting the "Resources" section of the Rain website after the conclusion of the presentation and will be archived on the Rain website.

About Rain Oncology Inc.

Rain Oncology Inc. is a late-stage precision oncology company developing therapies that target oncogenic drivers to genetically select patients it believes will most likely benefit. This approach includes using a tumor-agnostic strategy to select patients based on their tumors' underlying genetics rather than histology. Rain's lead product candidate, milademetan, is a small molecule, oral inhibitor of the MDM2-p53 complex that reactivates p53.

Media Contact

Jordyn Temperato

LifeSci Communications

jtemperato@lifescicomms.com

Investor Contact

Dan Ferry

LifeSci Advisors

+1.617.430.7576

daniel@lifesciadvisors.com



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