Aeglea Bio Therapeutics Inc
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Health Care : Biotechnology | Small Cap Blend

Aeglea BioTherapeutics, Inc. is a clinical-stage biotechnology company. It is focused on human enzyme therapeutics to treat people with rare metabolic diseases. Its lead product candidate is pegzilarginase, which is a recombinant human arginase 1 that enzymatically degrades the amino acid arginine to lower arginine levels in patients with Arginase 1 Deficiency. It has engineered pegzilarginase with modifications that enhance the stability and arginine-degrading activity of the enzyme in human plasma. Its second product candidate, AGLE-177, is a novel PEGylated ( polyethylene glycol) human enzyme engineered to degrade free homocysteine and homocystine in patients with Homocystinuria. The Company is evaluating Pegzilarginase in a global pivotal Phase III pivotal PEACE (Pegzilarginase Effect on Arginase one Deficiency Clinical Endpoints) trial and Phase I/II open-label extension trial. It is also conducting a Phase I/II clinical trial for the treatment of patients with Homocystinuria.

Price: Delayed
$0.4964

Day's Change: -0.0137 (-2.69%)

Bid: --

Ask: --

B/A Size: --

Day's High: 0.538

Day's Low: 0.4933

Volume (Light) Today's volume of 110,328 shares is on pace to be much lighter than AGLE's 10-day average volume of 843,322 shares.: 110,328

June 02, 2022
8:59 am ET	Aeglea BioTherapeutics Receives Refusal to File Letter from FDA for Pegzilarginase for the Treatment of Arginase 1 Deficiency Aeglea BioTherapeutics, Inc. (NASDAQ: AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics to benefit people with rare metabolic diseases, today announced that it received a Refusal to File (RTF)...(PR Newswire)
May 05, 2022
9:28 am ET	Aeglea BioTherapeutics Announces $45 Million Registered Direct Offering Priced at a Premium to Market Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics as innovative solutions for rare metabolic diseases, today announced that it has entered into a securities...(PR Newswire)
6:30 am ET	Aeglea BioTherapeutics Reports First Quarter 2022 Financial Results and Provides Program Updates Pegzilarginase BLA submitted to the FDA; if approved, pegzilarginase would be the first FDA-approved treatment for Arginase 1 Deficiency Additional PEACE data supporting potential efficacy of pegzilarginase presented at SIMD (PR Newswire)
April 12, 2022
8:30 am ET	Thinking about buying stock in Actinium Pharmaceuticals, BioCardia, Veru, Biodesix, or Aeglea Bio Therapeutics? InvestorsObserver issues critical PriceWatch Alerts for ATNM, BCDA, VERU, BDSX, and AGLE. https://mma.prnewswire.com/media/1333368/InvestorsObserver_Logo.jpg To see how InvestorsObserver's proprietary scoring system rates these stocks, view the...(PR Newswire)
6:01 am ET	Aeglea BioTherapeutics Submits BLA to FDA for Pegzilarginase for the Treatment of Arginase 1 Deficiency BLA submission provides FDA with all pegzilarginase program data to review in detail; Aeglea looks forward to working collaboratively with the FDA on next steps in the review process If approved, pegzilarginase would be the first FDA-approved...(PR Newswire)

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