Aeglea Bio Therapeutics IncChange company Symbol lookupSelect an option...AGLE Aeglea Bio Therapeutics IncNVAX Novavax IncEBIX Ebix IncFCRD First Eagle Alternative Capital BDC IncRWAY Runway Growth Finance CorpLITB LightInTheBox Holding Co LtdUEC Uranium Energy CorpNEE Nextera Energy IncMANT ManTech International CorpAMPE Ampio Pharmaceuticals IncGo
Aeglea BioTherapeutics, Inc. is a clinical-stage biotechnology company. The Company is focused on developing human enzyme therapeutics to benefit people with rare metabolic diseases. The Company’s product candidates include pegzilarginase and AGLE-177. The Company's lead product candidate, pegzilarginase, is a recombinant human arginase one that enzymatically degrades the amino acid arginine to lower arginine levels in patients with Arginase one Deficiency. Its engineered pegzilarginase with modifications that enhance the stability and arginine-degrading activity of the enzyme in human plasma. The Company is evaluating Pegzilarginase in a global pivotal Phase III PEACE (Pegzilarginase Effect on Arginase one Deficiency Clinical Endpoints) trial and in a Phase II open-label extension study for patients with Arginase One Deficiency. Its AGLE-177, is a novel PEGylated, or polyethylene glycol modified, human enzyme engineered to reduce Homocystinuria.
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