Aeglea Bio Therapeutics Inc
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Health Care : Biotechnology | Small Cap Value
Company profile

Aeglea BioTherapeutics, Inc. is a clinical-stage biotechnology company. It is focused on human enzyme therapeutics to treat people with rare metabolic diseases. Its lead product candidate is pegzilarginase, which is a recombinant human arginase 1 that enzymatically degrades the amino acid arginine to lower arginine levels in patients with Arginase 1 Deficiency. It has engineered pegzilarginase with modifications that enhance the stability and arginine-degrading activity of the enzyme in human plasma. Its second product candidate, AGLE-177, is a novel PEGylated ( polyethylene glycol) human enzyme engineered to degrade free homocysteine and homocystine in patients with Homocystinuria. The Company is evaluating Pegzilarginase in a global pivotal Phase III pivotal PEACE (Pegzilarginase Effect on Arginase one Deficiency Clinical Endpoints) trial and Phase I/II open-label extension trial. It is also conducting a Phase I/II clinical trial for the treatment of patients with Homocystinuria.

Closing Price
$0.5001
Day's Change
0.0769 (18.17%)
Bid
--
Ask
--
B/A Size
--
Day's High
0.54
Day's Low
0.4155
Volume
(Heavy Day)
Volume:
6,313,461

10-day average volume:
2,857,019
6,313,461
  • Prev Close
    0.4232
  • Today's Open
    0.44
  • Day's Range
    0.4155-0.54
  • Avg Vol (10-day)
    2.9M
  • Last (time)
    3:59p ET 12/02/22
  • Last (size)
    15
  • 52-Wk Range
    0.372 - 6.26
    LowHigh
  • (12/02/21 - 08/02/22)
    34.44%
  • 182.9%
  • Market Cap
    31.0M
  • Shares Outstanding
    61.5M
  • -1.15
  • --
  • No dividend
  • Ex-dividend Date
    No dividend
  • Dividend Pay Date
    No dividend
  • 1.7
  • 77.03
  • (% of float 11/15/22)
    1.96

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