Aerpio Pharmaceuticals Inc
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Health Care : Pharmaceuticals | Company profile

Aerpio Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on developing treatments for ocular disease. Its lead product candidate is AKB-9778. Its other two pipeline programs include AKB-4924 and ARP-1536. AKB-9778 is a small molecule activator of the Tie-2 pathway, which is being developed for the treatment of diabetic retinopathy (DR). AKB-4924 is a selective stabilizer of hypoxia-inducible factor-1 alpha (HIF-1alpha), which is being developed for the treatment of inflammatory bowel disease (IBD). ARP-1536 is a humanized monoclonal antibody directed at the same target as AKB-9778. ARP-1536 binds the extracellular domain of vascular endothelial protein tyrosine phosphatase (VE-PTP) inhibiting its ability to interact with Tie-2. As of April 14, 2017, the Company had completed a Phase II trial of AKB-9778 in 144 patients with diabetic macular edema. As of April 14, 2017, the Company had completed Phase Ia clinical trial in healthy volunteers for AKB-4924.

Day's Change
0.3719 (12.15%)
B/A Size
Day's High
Day's Low
(Heavy Day)

Today's volume of 263,819 shares is on pace to be much greater than ARPO's 10-day average volume of 105,436 shares.

  • Prev Close
  • Today's Open
  • Day's Range
  • Avg Vol (10-day)
  • Last (time)
    2:19p ET 01/18/19
  • Last (size)
  • 52-Wk Range
    1.56 - 5.25
  • (02/07/18 - 12/26/18)
  • 73.0%
  • Market Cap
  • Shares Outstanding
  • -0.44
  • --
  • No dividend
  • Ex-dividend
    No dividend
  • --
  • 27.70
  • (% of float 12/31/18)

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