Oncternal Therapeutics Inc
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Company profile

Oncternal Therapeutics, Inc., formerly GTX, Inc., is a clinical-stage biopharmaceutical company. The Company is focused on developing a pipeline of product candidates for the treatment of cancers. Its pipeline includes cirmtuzumab, TK-216 and chimeric antigen receptor T-cell (CAR-T). Its cirmtuzumab product candidate is an anti-receptor tyrosine kinase-like orphan receptor 1 (ROR1) monoclonal antibody. Cirmtuzumab is in a Phase-I/II clinical trial in combination with ibrutinib for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). TK216 is a small-molecule compound designed to inhibit the biological activity of E26 transformation-specific (ETS) oncoproteins. TK216 is being evaluated in combination with vincristine in a Phase-I clinical trial in patients with relapsed or refractory Ewing sarcoma. Its CAR-T product candidate targets ROR-1 and is in preclinical development as a treatment for hematologic cancers and solid tumors.

Postmarket

Last Trade
Delayed
$4.86
0.0051 (0.11%)
Bid
--
Ask
--
B/A Size
--

Market Hours

Closing Price
$4.86
Day's Change
-0.435 (-8.22%)
Bid close
--
Ask close
--
B/A Size
--
Day's High
5.28
Day's Low
4.61
Volume
(Heavy Day)
Volume:
57,565

10-day average volume:
32,103
57,565
  • Prev Close
    5.29
  • Today's Open
    5.28
  • Day's Range
    4.61-5.28
  • Avg Vol (10-day)
    32.1K
  • Last (time)
    3:59p ET 07/16/19
  • Last (size)
    10
  • 52-Wk Range
    0.74 - 25.60
    LowHigh
  • (09/13/18 - 12/24/18)
    556.08%
  • 335.4%
  • Market Cap
    116.8M
  • Shares Outstanding
    24.1M
  • -1.29
  • --
  • No dividend
  • Ex-dividend
    No dividend
  • 6.0
  • 22.50
  • (% of float 06/28/19)
    177.48

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